protean.bio → About us → Ladislav Burýšek

Doc. RNDr. Ladislav Burýšek, PhD.

CEO and Chief Scientific Officer
Doc. RNDr. Ladislav Burýšek, PhD.

Ladislav has many years experience of biotech research in Europe and USA. He has developed over a dozen of advanced IVD diagnostic tools and techniques and founded several successful companies.

Companies founded

Gen-Trend Ltd., Ceske Budejovice, Czech Republic 2005
Protean Ltd., Ceske Budejovice, Czech Republic 2008
Hutman Diagnostics AG, Basel, Switzerland 2011

Selection of developed IVD kits

Tick-borne pathogens PCR diagnostics Gen-Trend Ltd., Protean Ltd. 2005-2009
Stoma-Gene®, Cario-Gene® Protean Ltd. 2008-2009
ELISA-VIDTEST anti-Borrelia recombinant, LIA-VIDITEST VIDIA Ltd. 2009-2011
Endocardi-Gene®, Pneumo-Gene®, Meningo-Gene®, Fever-Gene® Hutman Diagnostics AG 2011-present

Education, Professional career

Faculty of Science, Charles University, Prague, Czech Republic 1984-1989
Laboratory of Immunology, Research Institute of Endocrinology, Prague, Czech Republic 1989-1991
Institute of Biochemistry and Medical chemistry, University of Bari, Bari, Italy 1993
Institute of Physiology, ASCR, Prague, Czech Republic 1991-1997
Johns Hopkins University, Oncology Center, Baltimore, Maryland, USA, postdoctoral stay 1997-2000
Department of Pharmacology of Natural Products and Clinical Pharmacology, University Hospital of Ulm, Ulm, Germany, postdoctoral stay, habilitation PD 2000-2005
Gen-Trend Ltd., Czech Republic, Co-Founder, Research & Development Director 2005-2008
Hutman Diagnostics AG, Switzerland, Co-Founder, Chief Scientific Officer 2011-2012
Protean Ltd., Czech Republic, Founder, Research & Development Director, CEO 2008-present

Publication list

Full publication list can be found at Google Scholar.



Grant projects

Grant Agency of the Czech Republic: Regulation of expression and function of pyrogenic cytokines in somatic cells. 1995 – 1997
National Institute of Health, USA: Cloning and characterization of novel Kaposi’s sarcoma herpes virus-encoded interferon regulatory factors. 1997 – 2000
University of Ulm, Germany: Cloning and characterization of human homologue of viral interferon regulatory factor 2 (vIRF-2). 2001 – 2003
Deutsches Forschunggesellschaft (DFG), Germany: Characterization of virus-induced transcription factors and regulation of gene expression of the host cell. 2002 – 2004
Ministry of Industry and Trade of the Czech Republic, Project Impulse: Development and manufacture of new generation of molecular biological diagnostic kits for parallel "macroarray" detection of human pathogens. 2004 – 2006
German-Israeli Project Cooperation (DIP), The German Ministry for Education and Research (BMBF), Germany: The role of intracellular IL-1 alpha in health and disease: mechanisms of action and therapeutic applications. 2005