|Purity||>95% by SDS PAGE|
HCMV pp65 is the most abundant late antigen of the cytomegalovirus infection.
Cytomegalovirus is a member of the herpes viruses. These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are coordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to viral replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be detected in the nuclei and cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein and is the most abundant of the late antigens.
ELISA, Western blot, LIA, Protein arrays
50mM Tris pH 7,5, 150mM NaCl, 1 mM EDTA, 5 mM DTT, 30% glycerol, may contain traces of glutathion. Protein conc. 1 mg/ml.
Highly immunoreactive protein containing pp65 epitopes from immunodominant region aa 297-510.
-80°C. Aliquot upon arrival.
For research use only. Not for use in diagnostic procedures.