CPB2 Toxoid (Clostridium perfringens toxin beta2)

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Introduction

Genetically modified nontoxic form of Clostridium perfringens toxin beta. Produced as toxoid with identical antigenic structures as wild type toxin in E. coli as recombinant GST-fusion protein.

Description

Beta2 toxin (CPB2) is widely reported as a potential contributor to C. perfringens related enteric diseases. It has no significant homology with beta toxin or other known bacterial toxins. CPB2 acts as a potential pore-forming toxin similar to other enterically-active clostridial toxins. The toxin was shown to be highly susceptible to proteolytic cleavage by trypsin.

Application

ELISA, Western blot, vaccine development

Purification method

Affinity chromatography

Formulation

PBS solution 1 mg/ml, contains 10 mM glutation.

Storage

-80°C