|Purity||>95% by SDS PAGE|
Genetically modified nontoxic form of Clostridium perfringens toxin beta-2. Produced as toxoid with identical antigenic response as wild-type toxin in E. coli as recombinant GST-fusion protein.
Clostridium perfringens beta toxin is a necrotizing agent and it induces hypertension by release of catecholamine. It is produced by Clostridium perfringens Type B and Type C strains. Beta toxin is susceptible to proteolytic cleavage particularly by trypsin, and is therefore highly lethal to infant mammals due to trypsin inhibitors presence in the colostrum.
ELISA, Western blot, vaccine development and testing
PBS solution 1 mg/ml, contains 10 mM glutation.
For research use only. Not for use in diagnostic procedures.